A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea

The bacterial and archaeal genomes that have been sequenced to date were chosen for sequencing based mainly on their physiology, which is fine but has resulted in a distinct phylogenetic bias. An alternative approach has been taken in the Genomic Encyclopedia of Bacteria and Archaea (GEBA) project, which advocates choosing genomes based on the organism's phylogenetic position, with the aim filling in the gaps in sequencing along on bacterial and archaeal branches of the tree of life. The value of this approach has been demonstrated by a pilot study of the genome sequences of 56 culturable species selected to maximize phylogenetic coverage. Analysis of the sequences provides insights into phylogenetics, protein…

• UD
  U.S. Department of Energy

  Awards: -AC02-05CH11231, DE-AC02-06NA25396, 05CH11231, AC02-05CH11231, DE-AC02, DE-AC02-05CH11231, AC52-07NA27344, DE-AC02-
• GA
  Gordon and Betty Moore Foundation
• DF
  Deutsche Forschungsgemeinschaft

  Awards: DE-AC02-05CH11231, DE-AC52-07NA27344
• OO
  Office of Science

  Awards: AC02-05CH11231, -AC02-05CH11231, DE-AC02, DE-AC52-07NA27344
• BA
  Biological and Environmental Research

  Awards: 05CH11231, DE-AC52-07NA27344, DE-AC02-05CH11231, AC02-05CH11231
• LL
  Lawrence Livermore National Laboratory

  Awards: DE-AC52-07NA27344, DE-AC02-05CH11231, AC52-07NA27344
• LB
  Lawrence Berkeley National Laboratory

  Awards: DE-AC02-05CH11231, 05CH11231, AC02-05CH11231, DE-AC52-07NA27344
• LA
  Los Alamos National Laboratory

  Awards: DE-AC52-07NA27344, DE-AC02-05CH11231