Comparative genomics of the lactic acid bacteria

Lactic acid-producing bacteria are associated with various plant and animal niches and play a key role in the production of fermented foods and beverages. We report nine genome sequences representing the phylogenetic and functional diversity of these bacteria. The small genomes of lactic acid bacteria encode a broad repertoire of transporters for efficient carbon and nitrogen acquisition from the nutritionally rich environments they inhabit and reflect a limited range of biosynthetic capabilities that indicate both prototrophic and auxotrophic strains. Phylogenetic analyses, comparison of gene content across the group, and reconstruction of ancestral gene sets indicate a combination of extensive gene loss and…

• UD
  U.S. Department of Energy

  Awards: -AC02-05CH11231, AC03-76SF00098, W-7405, 05CH11231, AC02-05CH11231, DE-AC02, 7405-Eng-48, DE-AC03, W-7405-Eng-48, W-7405-ENG-36, DE-AC02-
• UD
  U.S. Department of Agriculture

  Award: DE-AC02-05CH11231
• US
  Utah State University
• UA
  Utah Agricultural Experiment Station
• DM
  Dairy Management
• AV
  American Vineyard Foundation
• PP
  Pickle Packers International
• JG
  Joint Genome Institute

  Awards: DE-AC02-05CH11231, AC02-05CH11231
• NI
  National Institutes of Health

  Awards: GM55434, DE-AC02-05CH11231, DE-AC03-76SF00098
• OO
  Office of Science

  Awards: AC02-05CH11231, -AC02-05CH11231, DE-AC02, DE-AC03-76SF00098
• AR
  Agricultural Research Service
• BA
  Biological and Environmental Research

  Awards: 05CH11231, DE-AC02-05CH11231, AC02-05CH11231
• LL
  Lawrence Livermore National Laboratory

  Awards: -7405-Eng-48, DE-AC03-76SF00098, W-7405-ENG-36, DE-AC02-05CH11231, W-7405-Eng-48
• LB
  Lawrence Berkeley National Laboratory

  Awards: DE-AC03-76SF00098, 05CH11231, AC02-05CH11231
• LA
  Los Alamos National Laboratory

  Awards: W-7405-ENG-36, DE-AC02-05CH11231