A framework for human microbiome research
J. Craig Venter Institute · University of Maryland, College Park · +68 more institutions
Abstract
A variety of microbial communities and their genes (the microbiome) exist throughout the human body, with fundamental roles in human health and disease. The National Institutes of Health (NIH)-funded Human Microbiome Project Consortium has established a population-scale framework to develop metagenomic protocols, resulting in a broad range of quality-controlled resources and data including standardized methods for creating, processing and interpreting distinct types of high-throughput metagenomic data available to the scientific community. Here we present resources from a population of 242 healthy adults sampled at 15 or 18 body sites up to three times, which have generated 5,177 microbial taxonomic profiles…
Citation impact
- FWCI
- 80.61
- Percentile
- 100%
- References
- 21
Authors
270- RSRavi SankaCorresponding
J. Craig Venter Institute
- JBJohannes B. Goll
J. Craig Venter Institute
- JMJason Miller
J. Craig Venter Institute, University of Maryland, College Park
- LFLeslie Foster
University of Maryland, Baltimore, J. Craig Venter Institute, University of Baltimore
- KEKaren E. Nelson
University of Maryland, Baltimore, J. Craig Venter Institute, University of Baltimore
Topics & keywords
- Microbiome
- Human microbiome
- Computational biology
- Human Microbiome Project
- Data science
- Biology
- Computer science
- Bioinformatics
Funding
- NSNational Science FoundationAwards: IIS-0812111, 1053486, DE-AC02-05CH11231, DBI-1053486, 0812111
- HHHoward Hughes Medical InstituteAward: DE-AC02-05CH11231
- UDU.S. Department of EnergyAwards: -AC02-05CH11231, 05CH11231, AC02-05CH11231, DE-AC02, DE-AC02-05CH11231, DE-AC02-
- GAGordon and Betty Moore Foundation
- RURice University
- GIGladstone Institutes
- CACrohn's and Colitis Foundation
- CACrohn's and Colitis Foundation of Canada
- FWFonds Wetenschappelijk OnderzoekAward: DE-AC02-05CH11231
- VRVlaamse regering
- NINational Institutes of HealthAwards: U01HG004866, U54HG003067, U54HG004968, T32AI007528, U54HG003273, DBI-1053486, U54HG003079, U54HG004973, R01HG004885, P30DE020751, R21HG005811, DP2OD001500, DE-AC02-05CH11231, R01HG005969
- DTDefense Threat Reduction AgencyAwards: B104153I, DE-AC02-05CH11231, B084531I
- OOOffice of ScienceAwards: AC02-05CH11231, -AC02-05CH11231, DE-AC02
- HHHorace H. Rackham School of Graduate Studies, University of Michigan
- UNU.S. National Library of Medicine
- DODivision of Biological InfrastructureAward: DBI-1053486
- ARArmy Research OfficeAwards: DE-AC02-05CH11231, W911NF-11-1-0473, W911NF, W911NF-11
- LALos Alamos National LaboratoryAward: DE-AC02-05CH11231