reviewPhysiological ReviewsNov 19, 2015GREEN OA

Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility

University of Copenhagen · University of Turku · +5 more institutions

PubMed
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Abstract

It is predicted that Japan and European Union will soon experience appreciable decreases in their populations due to persistently low total fertility rates (TFR) below replacement level (2.1 child per woman). In the United States, where TFR has also declined, there are ethnic differences. Caucasians have rates below replacement, while TFRs among African-Americans and Hispanics are higher. We review possible links between TFR and trends in a range of male reproductive problems, including testicular cancer, disorders of sex development, cryptorchidism, hypospadias, low testosterone levels, poor semen quality, childlessness, changed sex ratio, and increasing demand for assisted reproductive techniques. We present…

Citation impact

936
total citations
FWCI
29.06
Percentile
100%
References
483
Citations per year

Authors

13

Topics & keywords

Keywords
  • Fertility
  • Semen quality
  • Infertility
  • Hypospadias
  • Demography
  • Physiology
  • Biology
  • Pregnancy
UN Sustainable Development Goals
  • No poverty
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