Regulation of glucose metabolism from a liver-centric perspective

Glucose homeostasis is tightly regulated to meet the energy requirements of the vital organs and maintain an individual's health. The liver has a major role in the control of glucose homeostasis by controlling various pathways of glucose metabolism, including glycogenesis, glycogenolysis, glycolysis and gluconeogenesis. Both the acute and chronic regulation of the enzymes involved in the pathways are required for the proper functioning of these complex interwoven systems. Allosteric control by various metabolic intermediates, as well as post-translational modifications of these metabolic enzymes constitute the acute control of these pathways, and the controlled expression of the genes encoding these enzymes is…

• NR
  National Research Foundation

  Award: 2015R1A5A1009024
• KU
  Korea University
• NR
  National Research Foundation of Korea

  Awards: 2015R1A2A1A01006687, NRF-2015R1A5A1009024, NRF-2012M3A9B6055345, 2015R1A5A1009024, NRF-2015R1A2A1A01006687