Probiotics, gut microbiota, and their influence on host health and disease
Consejo Superior de Investigaciones Científicas · Instituto de Productos Lácteos de Asturias · +2 more institutions
Abstract
The gastrointestinal tract of mammals hosts a high and diverse number of different microorganisms, known as intestinal microbiota. Many probiotics were originally isolated from the gastrointestinal tract, and they were defined by the Food and Agriculture Organization of the United Nations (FAO)/WHO as "live microorganisms which when administered in adequate amounts confer a health benefit on the host." Probiotics exert their beneficial effects on the host through four main mechanisms: interference with potential pathogens, improvement of barrier function, immunomodulation and production of neurotransmitters, and their host targets vary from the resident microbiota to cellular components of the gut-brain axis.…
Citation impact
- FWCI
- 34.47
- Percentile
- 100%
- References
- 140
Authors
6- BSBorja SánchezCorresponding
Consejo Superior de Investigaciones Científicas, Instituto de Productos Lácteos de Asturias
- SDSusana Delgado
Consejo Superior de Investigaciones Científicas, Instituto de Productos Lácteos de Asturias
- ABAitor Blanco‐Míguez
Universidade de Vigo
- ALAnália Lourenço
Universidade de Vigo, University of Minho
- MGMiguel Gueimonde
Consejo Superior de Investigaciones Científicas, Instituto de Productos Lácteos de Asturias
Topics & keywords
- Gut flora
- Host (biology)
- Disease
- Gut bacteria
- Biology
- Host factors
- Microbiology
- Medicine
- Zero hunger