Influence of diet on the gut microbiome and implications for human health

Singh, Rasnik; Chang, Hsin-Wen; Yan, Di; Lee, Kristina M.; Uçmak, Derya; Wong, Kirsten; Abrouk, Michael; Farahnik, Benjamin; Nakamura, Mio; Zhu, Tian Hao; Bhutani, Tina; Liao, Wilson

doi:10.1186/s12967-017-1175-y

reviewJournal of Translational MedicineApr 7, 2017GOLD OA

Influence of diet on the gut microbiome and implications for human health

RSRasnik Singh HCHsin-Wen Chang DYDi Yan KMKristina M. Lee DUDerya Uçmak

University of California, Los Angeles · University of California, San Francisco · +3 more institutions

PubMed

Indexed incrossrefdoajpubmed

Abstract

Recent studies have suggested that the intestinal microbiome plays an important role in modulating risk of several chronic diseases, including inflammatory bowel disease, obesity, type 2 diabetes, cardiovascular disease, and cancer. At the same time, it is now understood that diet plays a significant role in shaping the microbiome, with experiments showing that dietary alterations can induce large, temporary microbial shifts within 24 h. Given this association, there may be significant therapeutic utility in altering microbial composition through diet. This review systematically evaluates current data regarding the effects of several common dietary components on intestinal microbiota. We show that consumption…

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Topics & keywords

Topics

Keywords

Microbiome
Disease
Obesity
Type 2 diabetes
Immune system
Biology
Gut flora
Gut microbiome

UN Sustainable Development Goals

Good health and well-being

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