articleFrontiers in MicrobiologyNov 1, 2017GOLD OA

The Relationship among Tyrosine Decarboxylase and Agmatine Deiminase Pathways in Enterococcus faecalis

Instituto de Productos Lácteos de Asturias · Consejo Superior de Investigaciones Científicas · +1 more institution

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Abstract

Enterococci are considered mainly responsible for the undesirable accumulation of the biogenic amines (BA) tyramine and putrescine in cheeses. The biosynthesis of tyramine and putrescine has been described as a species trait in Enterococcus faecalis. Tyramine is formed by the decarboxylation of the amino acid tyrosine, by the tyrosine decarboxylase (TDC) route encoded in the tdc cluster. Putrescine is formed from agmatine by the agmatine deiminase (AGDI) pathway encoded in the agdi cluster. These biosynthesis routes have been independently studied, tyrosine and agmatine transcriptionally regulate the tdc and agdi clusters. The objective of the present work is to study the possible co-regulation among TDC and…

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