Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets
Tabriz University of Medical Sciences · Shiraz University of Medical Sciences · +7 more institutions
Abstract
Over the past few years, the cancer-related disease has had a high mortality rate and incidence worldwide, despite clinical advances in cancer treatment. The drugs used for cancer therapy, have high side effects in addition to the high cost. Subsequently, to reduce these side effects, many studies have suggested the use of natural bioactive compounds. Among these, which have recently attracted the attention of many researchers, quercetin has such properties. Quercetin, a plant flavonoid found in fresh fruits, vegetables and citrus fruits, has anti-cancer properties by inhibiting tumor proliferation, invasion, and tumor metastasis. Several studies have demonstrated the anti-cancer mechanism of quercetin, and…
Citation impact
- FWCI
- 19.40
- Percentile
- 100%
- References
- 202
Authors
15Topics & keywords
- Quercetin
- Cancer
- PI3K/AKT/mTOR pathway
- Signalling pathways
- Wnt signaling pathway
- Cancer research
- Metastasis
- Medicine
- Good health and well-being