reviewCancer Cell InternationalAug 15, 2022GOLD OA

Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets

Tabriz University of Medical Sciences · Shiraz University of Medical Sciences · +7 more institutions

PubMed
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Abstract

Over the past few years, the cancer-related disease has had a high mortality rate and incidence worldwide, despite clinical advances in cancer treatment. The drugs used for cancer therapy, have high side effects in addition to the high cost. Subsequently, to reduce these side effects, many studies have suggested the use of natural bioactive compounds. Among these, which have recently attracted the attention of many researchers, quercetin has such properties. Quercetin, a plant flavonoid found in fresh fruits, vegetables and citrus fruits, has anti-cancer properties by inhibiting tumor proliferation, invasion, and tumor metastasis. Several studies have demonstrated the anti-cancer mechanism of quercetin, and…

Citation impact

250
total citations
FWCI
19.40
Percentile
100%
References
202
Citations per year

Authors

15

Topics & keywords

Keywords
  • Quercetin
  • Cancer
  • PI3K/AKT/mTOR pathway
  • Signalling pathways
  • Wnt signaling pathway
  • Cancer research
  • Metastasis
  • Medicine
UN Sustainable Development Goals
  • Good health and well-being
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