reviewnpj Digital MedicineAug 26, 2022GOLD OA

The health digital twin to tackle cardiovascular disease—a review of an emerging interdisciplinary field

The University of Sydney · The George Institute for Global Health · +9 more institutions

PubMed
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Abstract

Potential benefits of precision medicine in cardiovascular disease (CVD) include more accurate phenotyping of individual patients with the same condition or presentation, using multiple clinical, imaging, molecular and other variables to guide diagnosis and treatment. An approach to realising this potential is the digital twin concept, whereby a virtual representation of a patient is constructed and receives real-time updates of a range of data variables in order to predict disease and optimise treatment selection for the real-life patient. We explored the term digital twin, its defining concepts, the challenges as an emerging field, and potentially important applications in CVD. A mapping review was…

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