review·Nature Reviews Clinical Oncology·Jan 26, 2024GREEN OA

BRAF — a tumour-agnostic drug target with lineage-specific dependencies

AJAphrothiti J. HanrahanCorresponding authorZCZiyu ChenNRNeal RosenDBDavid B. Solit

Memorial Sloan Kettering Cancer Center · Cornell University

PubMed
Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

Citation impact

119
total citations
FWCI
24.90
Percentile
100%
References
294
Citations per year

Authors

4
  • AJ
    Aphrothiti J. HanrahanCorresponding

    Memorial Sloan Kettering Cancer Center

  • ZC
    Ziyu Chen

    Memorial Sloan Kettering Cancer Center, Cornell University

  • NR
    Neal Rosen

    Memorial Sloan Kettering Cancer Center, Cornell University

  • DB
    David B. Solit

    Memorial Sloan Kettering Cancer Center, Cornell University

Topics & keywords

Topics
  • Primary topicMelanoma and MAPK Pathways100%
  • Colorectal Cancer Treatments and Studies100%
  • Cancer Mechanisms and Therapy99%
Keywords
  • Trametinib
  • Dabrafenib
  • MEK inhibitor
  • Cancer research
  • Medicine
  • Drug resistance
  • Vemurafenib
  • Population
No related works found for this paper.

Funding

  • EL
    Eli Lilly and Company
  • P
    Pfizer
    Award: P30 CA008748
  • MS
    Memorial Sloan-Kettering Cancer Center
    Award: CA008748
  • CF
    Cycle for Survival
    Awards: P30 CA008748, U54 OD020355
  • NI
    National Institutes of Health
    Awards: P30 CA008748, U54 OD020355, R01 CA229624
  • MA
    Marie-Josée and Henry R. Kravis Center for Molecular Oncology
    Award: P30 CA008748
  • NC
    National Cancer Institute
    Awards: CA008748, U54 OD020355, P30 CA008748