reviewJournal of Translational MedicineApr 30, 2024GOLD OA

Tribulations and future opportunities for artificial intelligence in precision medicine

King's College London · Foundation for the National Institutes of Health · +1 more institution

PubMed
Indexed incrossrefdoajpubmed

Abstract

Upon a diagnosis, the clinical team faces two main questions: what treatment, and at what dose? Clinical trials' results provide the basis for guidance and support for official protocols that clinicians use to base their decisions. However, individuals do not consistently demonstrate the reported response from relevant clinical trials. The decision complexity increases with combination treatments where drugs administered together can interact with each other, which is often the case. Additionally, the individual's response to the treatment varies with the changes in their condition. In practice, the drug and the dose selection depend significantly on the medical protocol and the medical team's experience. As…

Citation impact

135
total citations
FWCI
14.43
Percentile
100%
References
122
Citations per year

Authors

2

Topics & keywords

Keywords
  • Clinical trial
  • Protocol (science)
  • Clinical Practice
  • Health care
  • Precision medicine
  • Drug development
  • Population
  • Medicine
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