Glucagon-like peptide-1 receptor: mechanisms and advances in therapy
Shanghai Jiao Tong University · Shanghai Sixth People's Hospital · +1 more institution
Abstract
The glucagon-like peptide-1 (GLP-1) receptor, known as GLP-1R, is a vital component of the G protein-coupled receptor (GPCR) family and is found primarily on the surfaces of various cell types within the human body. This receptor specifically interacts with GLP-1, a key hormone that plays an integral role in regulating blood glucose levels, lipid metabolism, and several other crucial biological functions. In recent years, GLP-1 medications have become a focal point in the medical community due to their innovative treatment mechanisms, significant therapeutic efficacy, and broad development prospects. This article thoroughly traces the developmental milestones of GLP-1 drugs, from their initial discovery to…
Citation impact
- FWCI
- 234.78
- Percentile
- 100%
- References
- 522
Authors
7- ZZZhikai ZhengCorresponding
Shanghai Jiao Tong University, Shanghai Sixth People's Hospital
- ZYZong Yao
The University of Western Australia
- YMYiyang Ma
Shanghai Jiao Tong University, Shanghai Sixth People's Hospital
- YTYuchen Tian
Shanghai Jiao Tong University, Shanghai Sixth People's Hospital
- YPYidan Pang
Shanghai Jiao Tong University, Shanghai Sixth People's Hospital
Topics & keywords
- Bioinformatics
- Medicine
- Clinical trial
- Receptor
- Disease
- Neuroprotection
- Inflammation
- Neuroscience
- Good health and well-being