articleEuroMediterranean Biomedical JournalJan 12, 2026DIAMOND OA

CLINICAL ELECTRON MICROSCOPY IN THE STUDY OF HUMAN OVARIAN TISSUES

IGIlaria GiustiSBSerena BianchiSAStefania A. NottolaGMGuido MacchiarelliVDVincenza Dolo

University of L'Aquila · Sapienza University of Rome

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Abstract

Electron microscopy (EM) is a revolutionary imaging technique for obtaining high-resolution images of biological specimens in many fields, including the study of human ovarian tissues. EM, can be a powerful tool in many clinical fields, such as in therapeutic procedures for infertility. The success of Assisted Reproductive Technologies (ART), for example, is closely related to oocyte's quality, whose morphological features can be evaluated by EM to understand if the oocyte is mature, healthy and prone to fecundation. Moreover, EM studies are useful to demonstrate the responsiveness of the ovarian cells to environmental toxicants. EM can also be the starting point for the study of the release of extracellular…

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25
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Authors

5
  • IG
    Ilaria GiustiCorresponding

    University of L'Aquila

  • SB
    Serena Bianchi

    University of L'Aquila

  • SA
    Stefania A. Nottola

    Sapienza University of Rome

  • GM
    Guido Macchiarelli

    University of L'Aquila

  • VD
    Vincenza Dolo

    University of L'Aquila

Topics & keywords

Keywords
  • Electron microscope
  • Microscopy
  • Computational biology
  • Pathology
  • Materials science
  • Biology
  • Medicine
  • Physics
UN Sustainable Development Goals
  • Zero hunger
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