reviewSignal Transduction and Targeted TherapyFeb 20, 2025GOLD OA

Invasion and metastasis in cancer: molecular insights and therapeutic targets

Army Medical University · Xinqiao Hospital · +3 more institutions

PubMed
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Abstract

The progression of malignant tumors leads to the development of secondary tumors in various organs, including bones, the brain, liver, and lungs. This metastatic process severely impacts the prognosis of patients, significantly affecting their quality of life and survival rates. Research efforts have consistently focused on the intricate mechanisms underlying this process and the corresponding clinical management strategies. Consequently, a comprehensive understanding of the biological foundations of tumor metastasis, identification of pivotal signaling pathways, and systematic evaluation of existing and emerging therapeutic strategies are paramount to enhancing the overall diagnostic and treatment…

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