articleSignal Transduction and Targeted TherapyFeb 23, 2026GOLD OA

Cancer neuroscience: signaling pathways and new therapeutic strategies for cancer

University of Chinese Academy of Sciences · Northeastern University · +10 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

From a neuroscience perspective, cancer neuroscience has emerged as a subfield of cancer research. Presumable mechanisms underlying cancer-related neuronal activity (termed neurosciences) include the induction and modulation of signaling pathways that govern cell fate determination and emotional responses (anxiety and stress), such as structural molecules (synaptic structures and current transduction) and secretory substances (neurotransmitters, cytokines, hormones and neuropeptides). In the past 3 years, these neuronal activities, which can either promote cancer growth or be hijacked by cancer cells to support tumor survival and invasion, have been widely demonstrated to be closely related to cancer…

Citation impact

8
total citations
FWCI
134.97
Percentile
100%
References
485
Too recent for citation history.

Authors

8

Topics & keywords

Keywords
  • Cancer
  • Cancer cell
  • Signal transduction
  • Cell signaling
  • Mechanism (biology)
  • Cancer stem cell
UN Sustainable Development Goals
  • Good health and well-being
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