INFOGEST static in vitro simulation of gastrointestinal food digestion

Developing a mechanistic understanding of the impact of food structure and composition on human health has increasingly involved simulating digestion in the upper gastrointestinal tract. These simulations have used a wide range of different conditions that often have very little physiological relevance, and this impedes the meaningful comparison of results. The standardized protocol presented here is based on an international consensus developed by the COST INFOGEST network. The method is designed to be used with standard laboratory equipment and requires limited experience to encourage a wide range of researchers to adopt it. It is a static digestion method that uses constant ratios of meal to digestive…

• T
  Teagasc
• UD
  Universidade de Lisboa
• IN
  Institut National de la Recherche Agronomique
• BA
  Biotechnology and Biological Sciences Research Council

  Awards: BBS/E/F/00044427, BBS/E/F/000PR10345