Fermented Dairy Products as Precision Modulators of Gut Microbiota and Host Health: Mechanistic Insights, Clinical Evidence, and Future Directions
Zhejiang University of Science and Technology · University of Alberta · +2 more institutions
Abstract
Dairy products-encompassing yogurt, kefir, cheese, and cultured milk beverages-are emerging as versatile, food-based modulators of gut microbiota and host physiology. This review synthesizes mechanistic insights demonstrating how live starter cultures and their fermentation-derived metabolites (short-chain fatty acids, bioactive peptides, and exopolysaccharides) act synergistically to enhance microbial diversity, reinforce epithelial barrier integrity via upregulation of tight-junction proteins, and modulate immune signaling. Clinical evidence supports significant improvements in metabolic parameters (fasting glucose, lipid profiles, blood pressure) and reductions in systemic inflammation across metabolic…
Citation impact
- FWCI
- 42.22
- Percentile
- 100%
- References
- 146
Authors
10- YGYuan Gao
Zhejiang University of Science and Technology
- YLYanyan Liu
Zhejiang University of Science and Technology
- TMTingting Ma
Zhejiang University of Science and Technology
- QLQimeng Liang
Zhejiang University of Science and Technology
- JSJunqi Sun
Zhejiang University of Science and Technology
Topics & keywords
- Biology
- Host (biology)
- Gut flora
- Health benefits
- Biotechnology
- Computational biology
- Ecology
- Medicine